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The CADET Trial

Do you have depression?

Are you interested in a new potential treatment?

Kardinia Health is supporting a new treatment trial for depression run by Barwon Health and Deakin University.

The Aim

There is evidence from basic science and human studies that candesartan may have anti-depressant properties. The Deakin University led trial aims to assess if this commonly prescribed and well tolerated blood pressure medication, candesartan, may help people with major depressive disorder or bipolar disorder.

The trial aims to test if candesartan 16mg a day, in addition to usual treatment, helps to reduce symptoms of depression and improve general quality of life.

The Reason

Depression may, in part, be caused by inflammation and oxidative stress in the brain. Candesartan may help to reduce this inflammation and oxidative stress and protect neurons against stress. Candesartan may therefore be beneficial in reducing symptoms of depression.

Key Points for Participation

If you would like to receive more information about the study that might contribute to reducing depression or enquire about participating, please ask your Kardinia Health GP or contact the CADET Trial team on:

Phone: 0402 196 595